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精神分裂怎麼治?Part-V(主要缺鎂錳,缺鋅也有影響,而且病症可能由抑鬱症演變。) ...

已有 167 次閱讀2018-5-4 08:06 PM

Plasma magnesium (Mg) levels were estimated in 15 schizophrenic,
10 depressed, 6 manic and 6 presenile Alzheimer's disease patients and
 compared with those in 303 healthy controls. 
在15名精神分裂症患者,10名抑鬱症患者,6名躁狂症患者和6名早老性阿爾茨海默病患者中
評估血漿鎂(Mg)水平,並與303名健康對照者進行比較。
The schizophrenic and depressed patients showed lower levels, 
but the levels were normal in the other two groups. 
精神分裂症和抑鬱症患者的水平較低,但其他兩組的水平均正常

This is relevant to the risk of schizophrenia, as a 30–50% 
reduction in brain zinc content is demonstrated for early onset cases 
compared to control samples in postmortem samples
 (Kimura and Kumura, 1965; McLardy, 1973). 
這與精神分裂症的風險有關,因為與死後樣品中的對照樣品相比,
早期發病的腦鋅含量減少30-50%(Kimura and Kumura,1965; McLardy,1973)。

Selenium (Se), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe)
硒(Se),錳(Mn),銅(Cu),鋅(Zn)和鐵(Fe)
Plasma Cu concentrations were significantly higher (p < 0.01) 
and Mn and Fe concentrations were lower (p < 0.05 and p < 0.05, respectively) 
in schizophrenic patients than in controls. Se and Zn concentrations 
and protein levels did not differ between patients and healthy controls. 
精神分裂症患者的血漿Cu(銅)濃度顯著高於對照組(p <0.01),
Mn(錳)和Fe(鐵)濃度低於對照組(p <0.05和p <0.05)。 
Se(硒)和Zn(鋅)濃度和蛋白質水平在患者和健康對照之間沒有差異

由於
Therefore, NMDARs are important therapeutic targets for many CNS disorders 
including stroke, hypoxia, ischemia, head trauma, Huntington’s, Parkinson’s,
 and Alzheimer’s diseases, epilepsy, neuropathic pain, alcoholism, schizophrenia, 
and mood disorders.
因此,NMDARs是包括中風,缺氧,局部缺血,頭部創傷,亨廷頓舞蹈症,
帕金森氏症和阿爾茨海默病,癲癇,神經性疼痛,
酒精中毒,精神分裂症和心境障礙等許多中樞神經系統疾病的重要治療靶點
Zinc and magnesium, the potent antagonists of the NMDA receptor complex, 
are involved in the pathophysiology of depression and 
exhibit antidepressant activity.
是NMDA受體複合物的強效拮抗劑,參與抑鬱症的病理生理學並表現出抗抑鬱活性
Furthermore, lower concentrations (-9%) of magnesium (although not of zinc) 
were demonstrated in suicide tissue.
此外,在自殺組織中證明了較低濃度(-9%)的鎂(儘管不是鋅)
Manganese inhibits NMDA receptor channel function
抑制NMDA受體通道功能
因此
因為鎂鋅錳皆能抑制麩胺酸神經系統的N-methyl-D-aspartate(NMDA)受體
所以精神分裂可能和NMDA受體亢進有關
精神分裂可能是由抑鬱症演變而來,而且容易有自殘、自我傷害現象。(我的曾罹患嚴重精神分裂的家人就有這種症狀
)

總結以上
建議用含鎂鋅錳高的食物http://blog.eyny.com/blog-5788411-733718.html治療精神分裂症
也建議可以使用草莓口味的易開罐亞培安素(因為我的曾罹患嚴重精神分裂的家人喝原味不甜的易開罐亞培安素會吐
)

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